Collaborators

We are joining small vessel disease, extracellular matrix, neurovascular unit and vascular expertise across 5 UK institutions.

 
 
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Prof Karen Horsburgh

Karen is Professor of Neuroscience and Programme Organised for Hons. Neuroscience at the Centre for Discovery Brain Sciences at the University of Edinburgh. Karen obtained her PhD in Neuroscience at the University of Glasgow (UK) and as a Wellcome Trust University Award fellow moved to the University of Edinburgh. Karen is lead co-ordinator of the Alzheimer’s Society Doctoral Training Programme and an Alzheimer’s Research UK network in Scotland and a member of the MRC Dementia Platform UK Vascular Experimental Medicine committee. Karen’s research focuses on investigating the mechanisms underlying cognitive decline relevant to cerebral vascular disease and Alzheimer’s disease with the aim to identify novel targets for therapeutic strategies to slow the rate of cognitive decline and prevent dementia.

Email: karen.horsburgh@ed.ac.uk

 
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Dr Tom Van Agtmael

Tom is a Senior Lecturer and RCUK Fellow in Human Molecular Genetics at the Institute of Cardiovascular and Medical Sciences at the University of Glasgow. Tom obtained his PhD in Molecular Genetics at the Murdoch Childrens Research Institute in Melbourne (Australia). As an EU Marie Curie Fellow he identified the first vertebrate Col4a1 mutations and implicated type IV collagen in eye and kidney disease. His primary research interests include identifying molecular mechanisms that cause intracerebral haemorrhage, stroke, eye and kidney disease and the role of the extracellular matrix and collagen IV in health and disease.

Email: tom.vanagtmael@glasgow.ac.uk

 
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Dr Gaia Brezzo

Gaia is a Post Doctoral Research Fellow in Cerebrovascular Disease and Dementia at the Centre for Discovery Brain Sciences at the University of Edinburgh and an Affiliate Research Fellow at the Institute of Cardiovascular and Medical Sciences at the University of Glasgow. Gaia obtained her PhD in Neuroscience at the University of Sheffield (UK) investigating alterations in neurovascular coupling in disease models relevant to dementia and Alzheimer’s disease. Her primary research interests include investigating neurovascular function and neurovascular coupling in health and disease.

Email: gaia.brezzo@ed.ac.uk

 
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Prof Stuart Allan

Stuart is Professor of Neuroscience at the University of Manchester. He obtained his PhD in Biomedical Sciences from the University of Aberdeen and moved to Manchester as a Postdoctoral Research Associate. Stuart’s research is focused on understanding brain inflammation and cell death in stroke. His research interests include brain inflammation, cytokines and neuronal injury.

Email: stuart.allan@manchester.ac.uk

 
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Dr Sanjay Sinha

Sanjay is a British Heart Foundation Senior Clinical Research Fellow at the University of Cambridge. Sanjay completed his medical training in Cambridge followed by cardiology clinical training and a PhD in Manchester. Sanjay is also a consultant in Cardiology and he combines his research work with clinical duties at Addenbrooke’s Hospital, Cambridge, where he treats patients with a wide variety of cardiovascular diseases.

Email: ss661@cam.ac.uk

 
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Dr Alessandra Granata

Alessandra (Alex) is a Senior Research Associate at the department of Clinical Neurosciences at the University of Cambridge. Alex obtained her PhD in Cell and Developmental Biology at King’s College London. Alex’s research interests include the development of a iPSC-based model system for genetic forms of cerebral small vessel disease to uncover disease mechanisms and to identify new treatments for small vessel disease.

Email: ag686@cam.ac.uk

 
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Mary Goodwin

Mary is a PhD student in the Stroke Research Group, Department of Clinical Neurosciences at the University of Cambridge. Mary’s primary research interests, which form the basis of her PhD, include disease modelling using human iPSCs and the role of the blood-brain barrier in vascular disease. 

Email: mag82@cam.ac.uk

 
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Prof Tao Wang

Tao is Professor of Molecular Medicine at the University of Manchester. She obtained her PhD at the 3rd Hospital of Peking University Health Science Centre alongside her cardiology training. Tao is also is the Director of an international postgraduate Programme on Clinical Genetics and Genetic Counselling. Tao’s current work focuses on using iPSCs to model genetic small vessel diseases and explore how vascular factors contribute to neurodegeneration by looking into neurovascular interactions.

Email: tao.wang@manchester.ac.uk

 
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Prof Hugh Markus

Hugh is Professor of Stroke Medicine and Honorary Consultant Neurologist at the University of Cambridge. Hugh’s research focuses on applying molecular genetic and imaging techniques to investigate the pathogenesis of stroke, with a particular focus on cerebral small vessel disease. Hugh also runs a National clinical referral service for patients with the monogenic from of stroke CADASIL.

Email: hsm32@medschl.cam.ac.uk

 
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Dr Zameel Cader

Zameel (Zam) is Associate Professor of Clinical Neurosciences and Consultant Neurologist at the University of Oxford. He is also director of the Oxford Headache Centre and director of StemBANCC. Zam obtained his PhD in Neuroscience at Oxford and later completed his Clinical Neurology training. Zam’s research focuses on understanding the mechanisms underlying neurogenetic disorders including migraine and nerve degeneration.

Email: zameel.cader@ndcn.ox.ac.uk